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What to Expect From Knee RFA Treatment

September 19, 2025

A man is holding his leg in pain while experiencing discomfort in his knee.

Chronic knee pain can turn everyday activities into overwhelming challenges, keeping you from the life you love. If you have tried everything from physical therapy to medications with little success, there is a cutting-edge solution that could change everything — radiofrequency ablation (RFA) for knee pain.

This innovative, minimally invasive treatment is giving new hope to those struggling with persistent knee discomfort.

Here is everything you need to know about radiofrequency ablation for knee pain, so you can take the next step toward lasting relief.

Understanding Radiofrequency Ablation for Knee Pain

Radiofrequency ablation works by sending controlled heat through thin needles to the targeted nerves. The heat damages nerve fibers that carry pain signals. This process is also called radiofrequency neurotomy or rhizotomy.

The procedure focuses on sensory nerves around the knee joint. These nerves do not control muscle movement. Treating them reduces pain without affecting knee function or strength.

Doctors typically recommend knee RFA for patients with osteoarthritis or other degenerative joint conditions. The treatment works best when conservative options like medication and physical therapy have not provided adequate relief.

Ideal Candidates for Knee RFA

Not everyone with knee pain qualifies for radiofrequency ablation. Pain management doctors use specific criteria to determine suitable candidates.

Diagnostic Nerve Blocks

Patients must first receive diagnostic nerve blocks. These temporary injections use local anesthetics to numb target nerves. If the blocks provide significant pain relief, RFA may be effective.

Chronic Knee Pain Requirements

Chronic knee pain lasting six months or longer is typically required. The pain should interfere with daily activities and quality of life. Patients should have tried conservative treatments without success.

Medical Conditions That May Prevent RFA

Certain medical conditions may prevent RFA treatment. Active infections, bleeding disorders, or pregnancy can disqualify candidates. Your doctor will review your complete medical history before recommending the procedure.

Pre-Treatment Preparation

Proper preparation ensures the best possible outcomes from radiofrequency ablation for knee pain. Your pain management doctor will provide detailed instructions before the procedure.

Most patients need to stop taking blood-thinning medications several days before treatment. This includes aspirin, warfarin (Coumadin), and other anticoagulants. Your doctor will specify exactly when to stop these medications.

Arrange for someone to drive you home after the RFA procedure. You may feel drowsy from sedation or experience temporary weakness. Having support available reduces stress and ensures safety.

Wear comfortable, loose-fitting clothing on treatment day. Avoid jewelry and metal objects that might interfere with equipment. Bring a list of current medications and any relevant medical records.

The RFA Procedure Step by Step

Knee radiofrequency ablation typically takes 30 to 60 minutes and is performed in an outpatient setting with specialized equipment.

Preparation and Monitoring

You will lie comfortably on an examination table while the medical team monitors your vital signs. Light sedation is provided to help you relax while remaining awake and responsive.

Numbing the Treatment Area

The doctor cleans and numbs the treatment area with a local anesthetic to prevent pain during needle insertion. Multiple injection sites may be required to target all relevant nerves.

Needle Placement

Using X-ray guidance, the pain management physician places thin needles near the target nerves. The needles, containing electrodes, are positioned precisely to ensure effective treatment while protecting surrounding tissues.

Testing Needle Placement

Before ablation begins, the doctor tests each needle placement with mild electrical stimulation. This confirms proper positioning, and you may feel tingling or muscle twitching during this phase.

Ablation Process

The actual ablation takes only a few minutes per nerve. Controlled heat damages the nerve fibers while preserving important structures. Most patients experience minimal discomfort during this phase of RFA.

Immediate Post-Treatment Experience

Recovery after radiofrequency ablation starts immediately, with patients spending 30-60 minutes under observation. Temporary numbness or weakness in the treated leg is normal and resolves within hours.

Pain relief may be immediate or take weeks as nerves heal. Mild soreness at injection sites is common and can be managed with over-the-counter pain relievers.

Managing Pain and Discomfort

Manage post-procedure pain by following your healthcare team’s instructions.

  • Reduce swelling with ice packs for 15-20 minutes several times a day during the first 48 hours.
  • Avoid heat applications like heating pads or hot baths for a week, as they can delay healing.
  • Use over-the-counter pain relievers as directed, and contact your doctor if pain worsens or persists.

Expected Timeline for Results

Understanding the timeline for pain relief helps set realistic expectations. Radiofrequency ablation for knee pain does not provide instant results for everyone. Some patients see immediate improvement, while others may wait weeks. The treated nerves need time to stop sending pain signals.

Most patients notice significant improvement within two to eight weeks, with relief lasting six months to a year. Results vary based on factors like age, health, and the severity of knee damage. Some experience longer-lasting relief. Your doctor can give you a clearer idea based on your condition.

Potential Side Effects and Risks

Radiofrequency ablation for knee pain is generally safe but comes with some risks. Temporary numbness, weakness, or increased pain are common and usually resolve quickly.

Bleeding or bruising at the injection site is also common but should be checked if severe. Rare complications include long-lasting numbness or weakness.

Radiofrequency Ablation for Knee Pain in Central Florida

If you are struggling with persistent knee pain that limits your daily activities, it may be time to explore your options. The experienced team at Central Florida Spine & Pain specializes in advanced pain management techniques, including radiofrequency ablation for knee pain.

Our compassionate pain management specialist will evaluate your condition and develop a personalized treatment plan to help you regain comfort and mobility.

Contact us today at (321) 802-5021 to find out if radiofrequency ablation for knee pain is right for you. We look forward to serving you!

Filed Under: General Tagged With: advanced pain management techniques, degenerative joint conditions, Knee Pain, Osteoarthritis, Pain Management Specialist, radiofrequency ablation for knee pain, Radiofrequency Ablation for Knee Pain in Central Florida, rhizotomy

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At Central Florida Spine & Pain,  Dr. Giordano offers Interventional Pain Therapies and Minimally Invasive Treatments for acute and chronic pain conditions.